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KMID : 1036820190240041066
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Communication Sciences & Disorders
2019 Volume.24 No. 4 p.1066 ~ p.1076
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Characteristics of Vocal Loudness and Auditory Evoked Response in Patients with Parkinson’s Disease
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Choi Chul-Hee
Park Chae-Rim
Choi Seong-Hee
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Abstract
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Objectives: The objective of current study was to assess peripheral and central auditory functions in patients with Parkinson’s disease (PD), and furthermore, to explore whether electrophysiological responses in the brain relate to reduced vocal loudness in patients with PD.
Methods: A total of 24 subjects (12 normal and 12 IPD) participated. Pure tone audiometry and auditory evoked response as well as vocal loudness with sustained vowel /a/ and ‘Kaeul’ paragraph were measured. The stimulus level of 75 dB nHL was used to measure the latency and amplitude of waves I, III and V of auditory brainstem response (ABR) and Na, Pa, Nb, and Pb of auditory middle latency responses (AMLR) and P1, N1, P2, and N2 waves of auditory late latency responses (ALR).
Results: The results showed that the hearing thresholds of idiopathic PD (IPD) were not different from the normal group. Significant softer vocal loudness was observed in IPD. In AMLR, significantly delayed latency in wave Na, Pa and Nb and smaller Na-Pa amplitudes were revealed in the IPD group. These results imply that delayed latency and smaller amplitude of AMLR waves can be linked to thalamus dysfunction in individuals with IPD. Finally, a significantly negative correlation between vocal loudness and wave III latency was found, suggesting that the softer the vocal loudness, the longer the latency of wave III.
Conclusion: These results indicate that softer vocal loudness in individuals with IPD may be related to central auditory problems, not peripheral auditory dysfunction. Our findings suggest that electrophysiological methods provide valuable clinical information about sensory dysfunction in people with IPD.
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KEYWORD
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Parkinson’s disease, Hearing threshold, Auditory evoked response, Auditory middle latency response, Vocal loudness
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